Strain Identification and Verification

The complete genome of every HOWARU® strain has been sequenced and fully assembled to properly classify to the Genus, species, and strain level. Stringent process controls are maintained to ensure the commercial strain is identical to the strain that’s been studied

Genetic Safety Screening

Every HOWARU® probiotic strain is tested for virulence and toxigenic properties and the absence of antibiotic resistance transfer potential as a fundamental safety requirement established by regulatory bodies

Toxicity Testing

HOWARU® probiotic strains undergo toxicity testing to confirm safety for human consumption

Stability Assurance

HOWARU® probiotic strains are formulated for and evaluated across multiple format and temperature & humidity conditions to ensure viability through end of shelf-life

Survivability

HOWARU® strains have been tested for tolerance to stomach acid and bile salts

FDA Evaluated

HOWARU® probiotic strains are Generally Recognized As Safe (GRAS) and have been notified to the US FDA and accepted with no questions

Clinically Tested

HOWARU® probiotic strains are evaluated in human clinical trials to demonstrate safety and efficacy