Tablets account for nearly 35% of the global solid oral dosage form market, making them one of the most common nutrient delivery formats available. And it’s easy to see why: today’s consumers are looking for natural supplements that are efficient, easy-to-swallow and deliver results. For manufacturers seeking to meet these preferences, tablets are the ideal format since they’re cost-effective, versatile and shelf-stable.
But for all their commonality and flexibility, tablets still pose a challenge for dietary supplement manufacturers during production, especially during direct compression. Formulators must make sure that a compression mix flows to ensure a consistent tablet weight and that raw materials can be compressed and compacted into robust tablets – among other competing issues. The difficulty of processing natural vitamins and botanicals only compounds these problems, making formulation innovation to combat poor taste and increase flowability even more important.
Our team of global experts will work with you to determine how to effectively deliver nutritional ingredients—through immediate, sustained or delayed release—and pair them with plant-based formulation technologies and solutions to increase flowability, enhance consistency, improve quality and ditch unnecessary fillers. While simultaneously condensing the size of supplement tablets, coatings from our broad product portfolio can be utilized to mask the unpleasant bitter or sour tastes of natural ingredients.
Backed by decades of experience in the pharmaceutical space, our team understands the nuances of formulating dietary supplement tablets and is ready to help you every step of the way. Whether you’re looking to increase particle flow during direct compression or reduce your tablet size for easier swallowability, you can count on us. Consider DuPont your partner in creating high-quality, great-tasting tablets that exceed consumer expectations every time.
Our Solution |
Benefits |
---|---|
Ac-Di-Sol® SDW-802 |
Premium, non-GMO superdisintegrant that provides faster disintegration and dissolution at low use levels |
Accelerate® |
A superdisintegrant for achieving effective fast disintegration at low use levels in dietary supplements |
Aquacoat® ECD |
Aqueous dispersion of ethylcellulose that is used for sustained release coating for taste masking applications |
Aquateric® N100 |
Sustainable and plant-based coating solution that improve nutritional ingredient delivery and meets dietary supplement enteric disintegration requirements |
Avicel® / Endurance® MCC |
Microcrystalline cellulose binders that enable easier processing and improved physical properties of tablets. |
Avicel® CE-15 |
Improves sensory attributes by reducing grittiness, tooth packing and friability to create a creamier mouthfeel |
Avicel® SMCC |
Tailored microcrystalline cellulose binders for easier processing for powders, and better flow and superior compactibility for tablets. |
ETHOCEL™ |
Water-soluble polymers used as a granulation binder for improved tablet integrity and appearance |
Gelcarin® |
Naturally occurring hydrophilic polysaccharides extracted from red seaweed used to create rigid gel to thicken and stabilize formulations |
METHOCEL™ |
Plant-based, water-soluble polymers derived from cellulose used for:
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*Examples only and not representative of a complete list of products. Please note that regional differences in applicable laws and regulations may restrict the use of certain products in dietary supplements or different terminology definitions may apply. Please contact us for further information.
References
Purushottam R. Patil *, Vaibhav D. Bobade, Pankaj L. Sawant and Rajendra P. Marathe, Emerging Trends in compression coated tablet dosage forms a review.
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